With 3000 acres of pine forest to explore near Gainesville, this is one of those cases where maps point you to the forest without you knowing where to park, or even from which street. I added a parking lot to Google Maps to help you on your way! It is an off-street, earthen area that is fenced in and you'll have no problem with any type of vehicle.
The hiking itself is breathtaking, and there is more than immediately meets the eye. On my first stop, I only spent about half an hour, seeing little at first besides open fields speckled with the reserve's namesake, the longleaf pines. I dug in more during my second trip, a nice foggy morning in winter, and enjoyed each of my six miles through thick forest. The trails themselves are well maintained, with many choices to create your own journey of loops through red, white, and yellow trails. If you follow my route below, by either using the AllTrails App or the PDF, you will note a long, straight jaunt where I turn back. This is the blue trail. I don't recommend it as it seems to lead along a fence and straight back to the highway but away from the parking area.
On a weekend, I usually see one to three other cars and trucks parked here, but the trails and the area are expansive enough that you will have plenty of solitude by yourself or with a hiking partner. This is purely a hiking and camping area, with no amenities such as grills, picnic benches, or other facilities.